Changing my set changes the effect

Every so often, I change the infusion set for my insulin pump and my blood sugar rises unexpectedly. Sometimes I see this effect for an entire day. I follow the common advice of frequent monitoring and correction as needed.

Because this happens regularly with my Silhouette infusion sets, I began to ask why it would be happening. My endocrinologist suggested my basal rate needed to be adjusted, however, when I increase my basal I tend to be too low after the first day. At my next appointment with a nurse practitioner, I heard anecdotal accounts of problems with sites immediately after changing. I also read similar stories on other blogs
http://www.insulin-pumpers.org.uk/badsite/
http://www.diabetes-insulin-pump-therapy.com/high-blood-sugar.html

I really enjoy the UK Insulin Pumpers site because there is so much useful info that I can't seem to find anywhere except from people's personal experience. But I digress. Back to my original question - Why would you get high blood sugar from changing your site? From other diabetics and physicians, I found several possible explanations.

• The site could be too close to muscle or the infusion set slope is angled to steep and is too close to muscle causing higher blood sugar because insulin absorption is hindered.
• The site becomes swollen or irritated or at worst, infected, which causes inflammation and compromises your insulin activity and/or absorption.
• The site has hardened fat tissue, which prevents absorption.
• Site isn't taken very well and your body reacts to it negatively for a number of immune response reasons, which leads to inflammation and results in the same problems as above.

This problem doesn't happen all the time. Maybe 2-3 times per month out of 10-12 at the most. Usually if I give myself the infusion set and it really sings for a few minutes afterward, I know its going to act goofy for a day. Another case would be if its sensitive in that area when I press on the infusion set. I am now considering changing the type of infusion set I use to see if there is another set that may work better.


If you do call a helpline, I can give you an example of what you might hear, but please do call and do not rely on my personal account to make judgements on your own situation.

First, the insulin pump company asked me to perform a Pump Self-test and to make sure the tubing wasn't tangled or leaking. Ensure that the basal rates and bolus ratios are correct. Make sure the site isn't painful or problematic (is it red? swollen? is there blood? was it primed correctly? were there air bubbles?). You may need to change the set.

I found this MiniMed site helpful.
http://www.minimed.com/help/sitemanagement/index.html#a6
And there are also the National Institutes of Health and Center for Disease Control with useful sites too. http://www.cdc.gov/diabetes/ndep/index.htm
http://www.ndep.nih.gov/partners-community-organization/index.aspx
And I really like this book called "Insulin Pumping"... here's the website founded by the authors.
http://www.diabetesnet.com/pibook.php